Symbol Name ID |
C3ar1
complement component 3a receptor 1 MGI:1097680 |
Darker colors indicate more annotations |
Human Phenotypes | Asthma |
Disease(s) Associated with C3AR1 | |
asthma |
Mouse Phenotypes | abnormal T-helper 2 cell differentiation |
decreased eosinophil cell number |
decreased neutrophil cell number |
decreased lymphocyte cell number |
decreased osteoclast cell number |
abnormal eosinophil physiology |
impaired neutrophil recruitment |
decreased IgE level |
decreased IgG1 level |
abnormal T-helper 2 physiology |
increased circulating interleukin-1 beta level |
decreased circulating interleukin-6 level |
abnormal interleukin level |
abnormal immune system physiology |
abnormal adaptive immunity |
increased susceptibility to type I hypersensitivity reaction |
decreased interleukin-4 secretion |
decreased susceptibility to experimental autoimmune encephalomyelitis |
increased susceptibility to endotoxin shock |
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Availability | Mouse Genotype | |||||||||||||||||||
C3ar1tm1Cge/C3ar1tm1Cge | ||||||||||||||||||||
C3ar1tm1Raw/C3ar1tm1Raw | ||||||||||||||||||||
C3ar1tm1Raw/C3ar1+ |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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